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NLA 1

NLA-1 is a potent bioreductive cytotoxin and radiosensitizer belonging to the 2-nitroimidazole class. It intercalates into DNA with an affinity comparable to 9-aminoacridine, exhibiting significantly greater cytotoxicity than misonidazole (MISO) in hypoxic cellular and tumor models.

Product Specifications

CAS Number

140448-36-8

Smiles

Cl.[O-][N+] (=O) c1nccn1CCCNc1c2ccccc2nc2ccccc12

Molecular Formula

C19H18ClN5O2

Molecular Weight

383.84

Storage Conditions

-20°C

Notes

For research use only.

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