PF-6808472
PF-6808472 is a cell-permeable, covalent activity-based probe that selectively modifies conserved lysines in kinase ATP-binding sites, enabling the labeling of targets including CDK1, CDK2, and CDK4. It is used for kinase profiling, target engagement studies, and cell cycle research in both in vitro and cellular systems.
Product Specifications
CAS Number
2088112-70-1
Product Name Alternative
PF-6808472
Field of Research
Cell Biology
Purity
99.02% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.28 mM) ; DMSO:80 mg/mL (148.53 mM)
Smiles
O=C (NCC#C) C1=NC (=NC (=C1) NC2=NNC (=C2) C3CC3) N4CCN (CC5=CC=C (C=C5) S (=O) (=O) F) CC4
Molecular Formula
C25H27FN8O3S
Molecular Weight
538.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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