Piromelatine
Piromelatine is a multi-target small molecule acting as an MT1/MT2 and 5-HT1A/1D agonist and a 5-HT2B antagonist. Its research applications include studies of sleep, neuropathic pain, and depression, supported by in vivo models demonstrating antinociceptive, neuroprotective, and memory-enhancing effects.
Product Specifications
CAS Number
946846-83-9
Product Name Alternative
TRPChannel, TRP Channel, TRPVChannel, TRPV Channel, TRPV1, Sodium Channel, SodiumChannel, Piromelatine, P2X3, P2X Receptor, P2XReceptor, MTReceptor, MT Receptor, MT1 receptor, MT2 receptor, Nav1.7 channel, NEU-P 11, NEU-P11, NEU-P-11, 5HTReceptor, 5-HT2B, 5-HT1D, 5-HT1A, 5HT Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.83% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (12.81 mM) ; DMSO:100 mg/mL (320.18 mM)
Smiles
COc1ccc2[nH]cc (CCNC (=O) c3cc (=O) cco3) c2c1
Molecular Formula
C17H16N2O4
Molecular Weight
312.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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