BAY1217389
BAY 1217389 is a potent and selective small molecule inhibitor of the MPS1 kinase, exhibiting an IC50 of less than 10 nM. It is widely used in cancer research to study mitotic checkpoint signaling and has demonstrated antitumor efficacy in both cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
1554458-53-5
Product Name Alternative
Inhibitor, inhibit, Mps1, Monopolar spindle 1, BAY1217389, BAY-1217389, BAY 1217389
Field of Research
Signal Transduction
Purity
95.71% (May vary between batches)
Solubility
DMSO:93 mg/mL (165.63 mM) ; Ethanol:3 mg/mL (5.34 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (5.88 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
COc1ccc (Oc2cc (NCCC (F) (F) F) c3ncc (-c4ccc (C (=O) NC5CC5) c (C) c4) n3n2) c (F) c1F
Molecular Formula
C27H24F5N5O3
Molecular Weight
561.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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