SKLB 1028
SKLB 1028 (Ruserontinib) is an oral multikinase inhibitor targeting EGFR, FLT3, and Abl kinases. It demonstrates potent efficacy in FLT3-driven acute myeloid leukemia (AML) models in vitro and in vivo, and shows significant activity against chronic myeloid leukemia (CML) models harboring Abl mutations.
Product Specifications
CAS Number
1350544-93-2
Product Name Alternative
BcrAbl, Abl, EGFR, FLT3, SKLB1028, SKLB-1028, SKLB 1028, Ruserontinib
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.71% (May vary between batches)
Solubility
DMSO:50 mg/mL (112.73 mM)
Smiles
C (C) (C) N1C=2C (N=C1NC=3C=CC=NC3) =CN=C (NC4=CC=C (C=C4) N5CCN (C) CC5) N2
Molecular Formula
C24H29N9
Molecular Weight
443.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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