PCI-27483
PCI-27483 is a potent and selective inhibitor of activated coagulation factor VIIa (FVIIa) . It demonstrates antithrombotic activity in a baboon arterial thrombosis model and significantly inhibits the growth of BxPC3 pancreatic tumor xenografts in vivo, supporting its investigation in thrombosis and oncology research.
Product Specifications
CAS Number
871266-63-6
Product Name Alternative
Inhibit, PCI 27483, PCI27483, PCI-27483, Inhibitor, coagulation factor VIIa
Field of Research
Metabolism Research
Purity
98.45% (May vary between batches)
Solubility
DMSO:45 mg/mL (75.43 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.35 mM)
Smiles
NC (=N) c1ccc2[nH]c (nc2c1) -c1cc (CC (=O) N[C@@H] (CC (O) =O) C (O) =O) cc (c1O) -c1cc (ccc1O) S (N) (=O) =O
Molecular Formula
C26H24N6O9S
Molecular Weight
596.57
Storage Conditions
-20°C
Notes
For research use only.
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