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PCI-27483

PCI-27483 is a potent and selective inhibitor of activated coagulation factor VIIa (FVIIa) . It demonstrates antithrombotic activity in a baboon arterial thrombosis model and significantly inhibits the growth of BxPC3 pancreatic tumor xenografts in vivo, supporting its investigation in thrombosis and oncology research.

Product Specifications

CAS Number

871266-63-6

Product Name Alternative

Inhibit, PCI 27483, PCI27483, PCI-27483, Inhibitor, coagulation factor VIIa

Field of Research

Metabolism Research

Purity

98.45% (May vary between batches)

Solubility

DMSO:45 mg/mL (75.43 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.35 mM)

Smiles

NC (=N) c1ccc2[nH]c (nc2c1) -c1cc (CC (=O) N[C@@H] (CC (O) =O) C (O) =O) cc (c1O) -c1cc (ccc1O) S (N) (=O) =O

Molecular Formula

C26H24N6O9S

Molecular Weight

596.57

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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