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Taurolithocholic acid

Taurolithocholic acid 3-sulfate (TLC-S) is a potent bile acid that induces intracellular Ca2+ signaling in pancreatic acinar cells at low micromolar concentrations. It is a valuable research tool for studying bile acid receptor signaling, calcium-dependent cell physiology, and mechanisms relevant to pancreatitis in both in vitro and ex vivo experimental models.

Product Specifications

CAS Number

516-90-5

Product Name Alternative

Taurolithocholic acid, Lithocholic acid taurine conjugate, Lithocholyltaurine

Solubility

DMSO:13 mg/mL (26.88 mM)

Smiles

C[C@@]12[C@] ([C@]3 ([C@@] ([C@]4 (C) [C@] (CC3) (C[C@H] (O) CC4) [H]) (CC1) [H]) [H]) (CC[C@@]2 ([C@@H] (CCC (NCCS (=O) (=O) O) =O) C) [H]) [H]

Molecular Formula

C26H45NO5S

Molecular Weight

483.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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