UNIL-088
UNIL088 is a water-soluble phosphate ester prodrug of cyclosporine A designed for ocular delivery. It exhibits enhanced stability in acidic formulations and hydrolyzes rapidly under physiological conditions to release the active immunosuppressant, facilitating research into topical treatments for dry eye disease and corneal graft rejection in experimental models.
Product Specifications
CAS Number
473545-11-8
Smiles
[H][C@@]1 ([C@H] (OC (=O) CN (C) C (=O) [C@H] (COP (O) (O) =O) NC (=O) OC (C) OC (C) =O) [C@H] (C) C\C=C\C) N (C) C (=O) C (C (C) C) N (C) C (=O) [C@H] (CC (C) C) N (C) C (=O) [C@H] (CC (C) C) N (C) C (=O) [C@@H] (C) NC (=O) [C@H] (C) NC (=O) [C@H] (CC (C) C) N (C) C (=O) C (NC (=O) [C@H] (CC (C) C) N (C) C (=O) CN (C) C (=O) [C@H] (CC) NC1=O) C (C) C |@@:39,107|
Molecular Formula
C73H128N13O22P
Molecular Weight
1570.87
Storage Conditions
-20°C
Notes
For research use only.
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