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UNIL-088

UNIL088 is a water-soluble phosphate ester prodrug of cyclosporine A designed for ocular delivery. It exhibits enhanced stability in acidic formulations and hydrolyzes rapidly under physiological conditions to release the active immunosuppressant, facilitating research into topical treatments for dry eye disease and corneal graft rejection in experimental models.

Product Specifications

CAS Number

473545-11-8

Smiles

[H][C@@]1 ([C@H] (OC (=O) CN (C) C (=O) [C@H] (COP (O) (O) =O) NC (=O) OC (C) OC (C) =O) [C@H] (C) C\C=C\C) N (C) C (=O) C (C (C) C) N (C) C (=O) [C@H] (CC (C) C) N (C) C (=O) [C@H] (CC (C) C) N (C) C (=O) [C@@H] (C) NC (=O) [C@H] (C) NC (=O) [C@H] (CC (C) C) N (C) C (=O) C (NC (=O) [C@H] (CC (C) C) N (C) C (=O) CN (C) C (=O) [C@H] (CC) NC1=O) C (C) C |@@:39,107|

Molecular Formula

C73H128N13O22P

Molecular Weight

1570.87

Storage Conditions

-20°C

Notes

For research use only.

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