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VRT-325

VRT-325 is a corrector compound that addresses CFTR folding defects by facilitating NBD dimerization and TMD folding. It accelerates the repair of CFTR-mediated epithelial function in vitro, as demonstrated by its enhancement of wound healing rates in cystic fibrosis cell monolayer assays.

Product Specifications

CAS Number

815592-21-3

Product Name Alternative

CF106951, CF-106951, CF 106951, CFcor 325, CFcor325, CFcor-325, VRT 325, VRT 534, VRT325, VRT-325, VRT534, VRT-534

Field of Research

Pharmacology & Drug Discovery

Purity

98.07% (May vary between batches)

Solubility

DMSO:45 mg/mL (88.12 mM)

Smiles

O (C=1C2=C (N=C (C (C) N3CCN (S (=O) (=O) C4=CC=C (OC) C=C4) CC3) N1) C=CC=C2) C5CCCCC5

Molecular Formula

C27H34N4O4S

Molecular Weight

510.65

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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