VRT-325
VRT-325 is a corrector compound that addresses CFTR folding defects by facilitating NBD dimerization and TMD folding. It accelerates the repair of CFTR-mediated epithelial function in vitro, as demonstrated by its enhancement of wound healing rates in cystic fibrosis cell monolayer assays.
Product Specifications
CAS Number
815592-21-3
Product Name Alternative
CF106951, CF-106951, CF 106951, CFcor 325, CFcor325, CFcor-325, VRT 325, VRT 534, VRT325, VRT-325, VRT534, VRT-534
Field of Research
Pharmacology & Drug Discovery
Purity
98.07% (May vary between batches)
Solubility
DMSO:45 mg/mL (88.12 mM)
Smiles
O (C=1C2=C (N=C (C (C) N3CCN (S (=O) (=O) C4=CC=C (OC) C=C4) CC3) N1) C=CC=C2) C5CCCCC5
Molecular Formula
C27H34N4O4S
Molecular Weight
510.65
Storage Conditions
-20°C
Notes
For research use only.
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