Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Icosabutate

Icosabutate, an orally active ω-3 polyunsaturated fatty acid, is an aeicosapentaenoic acid (EPA) derivative. Icosabutate overcomes the drawbacks of unmodified EPA for liver targeting and improves insulin sensitivity, hepatic inflammation and fibrosis[1]. Icosabutate is well tolerated, and efficacious in lowering non-high-density lipoprotein cholesterol (non-HDL-C) levels in persistent hypertriglyceridemia [2].

Product Specifications

CAS Number

1253909-57-7

UNSPSC

12352211

Hazard Statement

H315-H319-H335-H400-H410

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/icosabutate.html

Purity

97.28

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCC(OCCCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)C(O)=O

Molecular Formula

C24H38O3

Molecular Weight

374.56

Precautions

P261-P264-P271-P273-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P391-P403+P233-P405-P501

References & Citations

[1]van den Hoek AM, et al. Icosabutate Exerts Beneficial Effects Upon Insulin Sensitivity, Hepatic Inflammation, Lipotoxicity, and Fibrosis in Mice.Hepatol Commun. 2019 Dec 24;4 (2) :193-207.|[2]Kastelein JJ, et al. Icosabutate, a Structurally Engineered Fatty Acid, Improves the Cardiovascular Risk Profile in Statin-Treated Patients with Residual Hypertriglyceridemia.Cardiology. 2016;135 (1) :3-12.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Tissue Protein Lysate, Stomach
CP565588 150 µg

Tissue Protein Lysate, Stomach

Sign In for Pricing
View Details
Climatic Chamber BCCL-1303
BCCL-1303 1 Unit

Climatic Chamber BCCL-1303

Sign In for Pricing
View Details
ALF (GTF2A1L) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4B4]
TA810961AM 100 µL

ALF (GTF2A1L) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI4B4]

Sign In for Pricing
View Details
Diethyl Sulfide
TRC-D445005-50G 50 g

Diethyl Sulfide

Sign In for Pricing
View Details
Slc15a5 Mouse Gene Knockout Kit (CRISPR)
KN515881 1 Kit

Slc15a5 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
CD30 (TNFRSF8) Mouse Monoclonal Antibody [Clone ID: MEM-268]
AM03094RP-N 100 Tests

CD30 (TNFRSF8) Mouse Monoclonal Antibody [Clone ID: MEM-268]

Sign In for Pricing
View Details