Icosabutate
Icosabutate, an orally active ω-3 polyunsaturated fatty acid, is an aeicosapentaenoic acid (EPA) derivative. Icosabutate overcomes the drawbacks of unmodified EPA for liver targeting and improves insulin sensitivity, hepatic inflammation and fibrosis[1]. Icosabutate is well tolerated, and efficacious in lowering non-high-density lipoprotein cholesterol (non-HDL-C) levels in persistent hypertriglyceridemia [2].
Product Specifications
CAS Number
1253909-57-7
UNSPSC
12352211
Hazard Statement
H315-H319-H335-H400-H410
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/icosabutate.html
Purity
97.28
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCC(OCCCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)C(O)=O
Molecular Formula
C24H38O3
Molecular Weight
374.56
Precautions
P261-P264-P271-P273-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P391-P403+P233-P405-P501
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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