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H-1152 dihydrochloride

H-1152 dihydrochloride is a potent and selective ROCK inhibitor with an IC50 of 12 nM. It is widely used in cardiovascular and neurological research to study cell motility, cytoskeletal dynamics, and vascular tone in both cellular and animal models.

Product Specifications

CAS Number

871543-07-6

Product Name Alternative

ROCK2, H1152, H-1152, H-1152 2HCl, H1152 Dihydrochloride, H1152 dihydrochloride, H-1152 Dihydrochloride, H-1152 dihydrochloride, H 1152, H 1152 dihydrochloride, H 1152 Dihydrochloride

Field of Research

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.42% (May vary between batches)

Solubility

DMSO:40 mg/mL (101.95 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.1 mM) ; H2O:32.1 mg/mL (81.82 mM)

Smiles

Cl.Cl.C[C@H]1CNCCCN1S (=O) (=O) c1cccc2cncc (C) c12

Molecular Formula

C16H23Cl2N3O2S

Molecular Weight

392.34

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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