H-1152 dihydrochloride
H-1152 dihydrochloride is a potent and selective ROCK inhibitor with an IC50 of 12 nM. It is widely used in cardiovascular and neurological research to study cell motility, cytoskeletal dynamics, and vascular tone in both cellular and animal models.
Product Specifications
CAS Number
871543-07-6
Product Name Alternative
ROCK2, H1152, H-1152, H-1152 2HCl, H1152 Dihydrochloride, H1152 dihydrochloride, H-1152 Dihydrochloride, H-1152 dihydrochloride, H 1152, H 1152 dihydrochloride, H 1152 Dihydrochloride
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.42% (May vary between batches)
Solubility
DMSO:40 mg/mL (101.95 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.1 mM) ; H2O:32.1 mg/mL (81.82 mM)
Smiles
Cl.Cl.C[C@H]1CNCCCN1S (=O) (=O) c1cccc2cncc (C) c12
Molecular Formula
C16H23Cl2N3O2S
Molecular Weight
392.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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