BTK inhibitor 1 (Compound 27)
Compound 27 is a potent and selective BTK inhibitor, demonstrating an IC50 of 0.11 nM against the enzyme and 2 nM for inhibiting B-cell activation in human whole blood assays. This small molecule is a valuable research tool for studying B-cell signaling and related autoimmune or hematological malignancies in both in vitro and in vivo models.
Product Specifications
CAS Number
2230724-66-8
Product Name Alternative
BTK inhibitor 1, BTK inhibitor 1 (Compound 27), BTK
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction
Purity
98.24% (May vary between batches)
Solubility
DMSO:4.75 mg/mL (10.01 mM)
Smiles
FC=1C=C (C2=C3C (NC (=C3) C=4C=NN (C) C4) =NC=N2) C=CC1CNC (=O) C=5N=C (C (C) (C) C) ON5
Molecular Formula
C24H23FN8O2
Molecular Weight
474.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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