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(-) -Sitagliptin Carbamoyl Glucuronide

(-) -Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the antidiabetic drug (-) -sitagliptin, formed via N-carbamoyl glucuronidation. It has been identified in the plasma of rats and dogs, serving as a reference standard for pharmacokinetic and metabolic studies of DPP-4 inhibitors in both in vivo and in vitro research.

Product Specifications

CAS Number

940002-59-5

Field of Research

Pharmacology & Drug Discovery, Protein Biochemistry

Smiles

O[C@@H]1[C@@H] (O) [C@H] (OC (=O) N[C@@H] (CC (=O) N2CCn3c (C2) nnc3C (F) (F) F) Cc2cc (F) c (F) cc2F) O[C@@H] ([C@H]1O) C (O) =O

Molecular Formula

C23H23F6N5O9

Molecular Weight

627.453

Storage Conditions

-20°C

Notes

For research use only.

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