HPI-1 (hydrate)
HPI-1 hydrate is a selective Hedgehog pathway inhibitor (IC50=1.5 μM) that acts downstream of Smoothened, blocking Gli-mediated signaling and proliferation. It is used in vitro and in vivo to study Hh-driven processes, including cancer and developmental biology research, without affecting Wnt signaling at relevant concentrations.
Product Specifications
CAS Number
1262770-72-8
Smiles
O=C (OCCOC) C1=C (NC2=C (C (=O) CC (C=3C=CC=CC3OC) C2) C1C=4C=CC=C (O) C4) C.O
Molecular Formula
C27H31NO7
Molecular Weight
481.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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