VT107
VT-107 is a potent and selective inhibitor of TEAD autopalmitoylation, effectively disrupting the Hippo signaling pathway. This small molecule is a valuable research tool for studying oncogenic YAP/TAZ-TEAD activity in cancer biology, with applications in both in vitro cellular assays and in vivo xenograft models for therapeutic exploration.
Product Specifications
CAS Number
2417718-63-7
Product Name Alternative
YAP–TEAD, VT 107, VT107, VT-107
Field of Research
Stem Cell & Developmental Biology
Purity
98.43% (May vary between batches)
Solubility
DMSO:260 mg/mL (597.1 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.48 mM)
Smiles
C[C@H] (NC (=O) c1ccc2c (cccc2c1) -c1ccc (cc1) C (F) (F) F) c1cccc (N) n1
Molecular Formula
C25H20F3N3O
Molecular Weight
435.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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