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VT107

VT-107 is a potent and selective inhibitor of TEAD autopalmitoylation, effectively disrupting the Hippo signaling pathway. This small molecule is a valuable research tool for studying oncogenic YAP/TAZ-TEAD activity in cancer biology, with applications in both in vitro cellular assays and in vivo xenograft models for therapeutic exploration.

Product Specifications

CAS Number

2417718-63-7

Product Name Alternative

YAP–TEAD, VT 107, VT107, VT-107

Field of Research

Stem Cell & Developmental Biology

Purity

98.43% (May vary between batches)

Solubility

DMSO:260 mg/mL (597.1 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.48 mM)

Smiles

C[C@H] (NC (=O) c1ccc2c (cccc2c1) -c1ccc (cc1) C (F) (F) F) c1cccc (N) n1

Molecular Formula

C25H20F3N3O

Molecular Weight

435.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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