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Dynapyrazole A

Dynapyrazole A is a small molecule inhibitor of microtubule-associated dynein motors, with IC50 values of 2.3 and 2.6 μM for dynein 1 and 2, respectively. It also suppresses Hedgehog signaling with an IC50 of 1.9 μM, making it a useful chemical probe for studying cytoskeletal dynamics and developmental signaling pathways in cellular models.

Product Specifications

CAS Number

2226517-75-3

Product Name Alternative

Dynamin, Dynapyrazole A

Field of Research

Signal Transduction

Purity

97.44% (May vary between batches)

Solubility

DMSO:22.5 mg/mL (46.23 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.11 mM)

Smiles

Clc1ccc (cc1) C1 (CC1) c1nn2c ([nH]c (=O) c3cc (I) ccc23) c1C#N

Molecular Formula

C20H12ClIN4O

Molecular Weight

486.69

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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