Dynapyrazole A
Dynapyrazole A is a small molecule inhibitor of microtubule-associated dynein motors, with IC50 values of 2.3 and 2.6 μM for dynein 1 and 2, respectively. It also suppresses Hedgehog signaling with an IC50 of 1.9 μM, making it a useful chemical probe for studying cytoskeletal dynamics and developmental signaling pathways in cellular models.
Product Specifications
CAS Number
2226517-75-3
Product Name Alternative
Dynamin, Dynapyrazole A
Field of Research
Signal Transduction
Purity
97.44% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (46.23 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.11 mM)
Smiles
Clc1ccc (cc1) C1 (CC1) c1nn2c ([nH]c (=O) c3cc (I) ccc23) c1C#N
Molecular Formula
C20H12ClIN4O
Molecular Weight
486.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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