GSK-3β inhibitor 8
GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent, selective thienopyrimidine-based compound with an IC50 of 64 nM. It acts as a negative regulator of Wnt signaling and has been shown to stimulate β-cell proliferation in research models, supporting its use in diabetes and regenerative biology studies.
Product Specifications
CAS Number
1139875-74-3
Product Name Alternative
Wnt/β-catenin, Wnt/betacatenin, Wnt/b-catenin, Wnt, βcatenin, GSK-3b inhibitor 8, GSK-3beta inhibitor 8, GSK3beta Inhibitor XVIII, GSK3b Inhibitor XVIII, GSK-3β, GSK-3β inhibitor 8, GSK3β Inhibitor XVIII, GSK3, betacatenin, beta-catenin, bcatenin
Field of Research
Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.46% (May vary between batches)
Solubility
DMSO:Soluble
Smiles
C (=O) (C1=C (Cl) C=C (NC=2N=C (C=CN2) C3=CC=CS3) C=C1) N4CCN (C) CC4
Molecular Formula
C20H20ClN5OS
Molecular Weight
413.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940745-500 1x 500 µL
CD45 / LCA (2B11 + PD7/26), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740525-500 1x 500 µL
CD63 (MX-49.129.5), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740806-100 1x 100 µL
TYRP1 (Tyrosinase Related Protein 1) (TA99), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940026-100 1x 100 µL
ACTH (Adrenocorticotrophic Hormone) (AH26), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 