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GSK-3β inhibitor 8

GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent, selective thienopyrimidine-based compound with an IC50 of 64 nM. It acts as a negative regulator of Wnt signaling and has been shown to stimulate β-cell proliferation in research models, supporting its use in diabetes and regenerative biology studies.

Product Specifications

CAS Number

1139875-74-3

Product Name Alternative

Wnt/β-catenin, Wnt/betacatenin, Wnt/b-catenin, Wnt, βcatenin, GSK-3b inhibitor 8, GSK-3beta inhibitor 8, GSK3beta Inhibitor XVIII, GSK3b Inhibitor XVIII, GSK-3β, GSK-3β inhibitor 8, GSK3β Inhibitor XVIII, GSK3, betacatenin, beta-catenin, bcatenin

Field of Research

Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.46% (May vary between batches)

Solubility

DMSO:Soluble

Smiles

C (=O) (C1=C (Cl) C=C (NC=2N=C (C=CN2) C3=CC=CS3) C=C1) N4CCN (C) CC4

Molecular Formula

C20H20ClN5OS

Molecular Weight

413.92

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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