SAR502250
SAR502250 is a potent, brain-penetrant, and orally active inhibitor of GSK-3β, demonstrating an IC50 of 12 nM. It shows antidepressant-like effects in preclinical models and is investigated for Alzheimer's disease, with studies exploring its neuroprotective mechanisms in vitro and in vivo.
Product Specifications
CAS Number
503860-57-9
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Smiles
Cn1c (nc (cc1=O) -c1ccncn1) N1CCO[C@H] (C1) c1ccc (F) cc1
Molecular Formula
C19H18FN5O2
Molecular Weight
367.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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