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SAR502250

SAR502250 is a potent, brain-penetrant, and orally active inhibitor of GSK-3β, demonstrating an IC50 of 12 nM. It shows antidepressant-like effects in preclinical models and is investigated for Alzheimer's disease, with studies exploring its neuroprotective mechanisms in vitro and in vivo.

Product Specifications

CAS Number

503860-57-9

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Smiles

Cn1c (nc (cc1=O) -c1ccncn1) N1CCO[C@H] (C1) c1ccc (F) cc1

Molecular Formula

C19H18FN5O2

Molecular Weight

367.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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