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RBPJ Inhibitor-1

RBPJ Inhibitor-1 (RIN1) is a small molecule that disrupts the RBPJ-SHARP interaction, thereby blocking canonical NOTCH signaling and proliferation in tumor cells. It serves as a valuable research tool for investigating NOTCH pathway biology in both cellular and animal models of cancer and other diseases.

Product Specifications

CAS Number

2682114-39-0

Product Name Alternative

Notch, Gammasecretase, RIN 1, RIN1, RIN-1, RBPJ Inhibitor-1

Field of Research

Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry, Stem Cell & Developmental Biology

Purity

99.58% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (16.06 mM) ; DMSO:225 mg/mL (722.75 mM)

Smiles

O (C1=C (C (N) =O) C=CC (=C1) C=2N (C) N=CC2) C3=C (F) C=CC=C3

Molecular Formula

C17H14FN3O2

Molecular Weight

311.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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