RBPJ Inhibitor-1
RBPJ Inhibitor-1 (RIN1) is a small molecule that disrupts the RBPJ-SHARP interaction, thereby blocking canonical NOTCH signaling and proliferation in tumor cells. It serves as a valuable research tool for investigating NOTCH pathway biology in both cellular and animal models of cancer and other diseases.
Product Specifications
CAS Number
2682114-39-0
Product Name Alternative
Notch, Gammasecretase, RIN 1, RIN1, RIN-1, RBPJ Inhibitor-1
Field of Research
Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry, Stem Cell & Developmental Biology
Purity
99.58% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (16.06 mM) ; DMSO:225 mg/mL (722.75 mM)
Smiles
O (C1=C (C (N) =O) C=CC (=C1) C=2N (C) N=CC2) C3=C (F) C=CC=C3
Molecular Formula
C17H14FN3O2
Molecular Weight
311.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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