SB 202190 hydrochloride
SB 202190 hydrochloride is the salt form of the selective p38 MAPK inhibitor SB 202190. This cell-permeable compound inhibits p38α and p38β2 isoforms and has been utilized in vitro to study inflammation, apoptosis, and cardiomyocyte differentiation from stem cells, as well as in vivo tumor models.
Product Specifications
CAS Number
350228-36-3
Product Name Alternative
SB 202190 HCl, SB 202190 hydrochloride, SB202190 Hydrochloride, SB-202190 Hydrochloride
Field of Research
Cell Biology, Signal Transduction
Purity
99.99% (May vary between batches)
Solubility
DMF:10 mg/mL (27.19 mM) ; DMSO:60 mg/mL (163.13 mM) ; Ethanol:PBS (pH 7.2) (1:10) :< 1 mg/mL, insoluble; Ethanol:10 mg/mL (27.19 mM)
Smiles
Cl.FC=1C=CC (=CC1) C=2NC (=NC2C=3C=CN=CC3) C=4C=CC (O) =CC4
Molecular Formula
C20H15ClFN3O
Molecular Weight
367.8
Storage Conditions
-20°C
Notes
For research use only.
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