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Cuspin-1

Cuspin-1 is a small molecule that upregulates Survival of Motor Neuron (SMN) protein levels by activating the Ras-Raf-MEK-ERK pathway to enhance SMN translation. It has demonstrated efficacy in vitro, increasing SMN by 50% in SMA patient fibroblasts, and serves as a valuable research tool for studying SMA mechanisms and therapeutic strategies.

Product Specifications

CAS Number

337932-29-3

Field of Research

Signal Transduction

Smiles

Cc1ccc (cc1) C (=O) c1cncc (Br) c1

Molecular Formula

C13H10BrNO

Molecular Weight

276.13

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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