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NO-Losartan A

Losartan is a potent AT1 receptor antagonist (Ki 5-20 nM) used to study hypertension and renal protection. Its NO-donor hybrid, NO-losartan A, combines AT1 blockade with nitric oxide-mediated vasodilation, making it a valuable tool for cardiovascular research in both in vitro and in vivo models.

Product Specifications

CAS Number

791122-48-0

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

C (N1C (COC (=O) C2=CC (CON (=O) =O) =CC=C2) =C (Cl) N=C1CCCC) C3=CC=C (C=C3) C4=C (C=CC=C4) C=5NN=NN5

Molecular Formula

C30H28ClN7O5

Molecular Weight

602.04

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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