NO-Losartan A
Losartan is a potent AT1 receptor antagonist (Ki 5-20 nM) used to study hypertension and renal protection. Its NO-donor hybrid, NO-losartan A, combines AT1 blockade with nitric oxide-mediated vasodilation, making it a valuable tool for cardiovascular research in both in vitro and in vivo models.
Product Specifications
CAS Number
791122-48-0
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (N1C (COC (=O) C2=CC (CON (=O) =O) =CC=C2) =C (Cl) N=C1CCCC) C3=CC=C (C=C3) C4=C (C=CC=C4) C=5NN=NN5
Molecular Formula
C30H28ClN7O5
Molecular Weight
602.04
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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