AMP-Deoxynojirimycin
AMP-Deoxynojirimycin (AMP-DNM) is a potent inhibitor of ceramide glucosyltransferase and glucosylceramidase (GCase), effectively blocking glucosylceramide (GlcCer) biosynthesis. This small molecule is utilized in research models of metabolic and neurological disorders, including diabetes and Parkinson's disease, to investigate glycosphingolipid metabolism in both cellular and animal studies.
Product Specifications
CAS Number
216758-20-2
Product Name Alternative
AMP Deoxynojirimycin, AMPDeoxynojirimycin, AMP-Deoxynojirimycin, AMP-DNM, Glucosidase, glucosylceramide synthase
Field of Research
Metabolism Research
Purity
>99.99% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (5.03 mM) ; DMF:50 mg/mL (125.77 mM) ; DMSO:40 mg/mL (100.62 mM) ; Ethanol:20 mg/mL (50.31 mM) ; Ethanol:PBS (pH 7.2) (1:1) :0.5 mg/mL (1.26 mM)
Smiles
C (OCCCCCN1[C@H] (CO) [C@@H] (O) [C@H] (O) [C@@H] (O) C1) C23CC4CC (C2) CC (C3) C4
Molecular Formula
C22H39NO5
Molecular Weight
397.55
Storage Conditions
-20°C
Notes
For research use only.
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