SR 1903
SR 1903 is a dual modulator acting as an inverse agonist of RORγ and an agonist of LXR, with additional binding to PPARγ. It suppresses pro-inflammatory pathways in vitro and demonstrates efficacy in mouse models of arthritis and obesity by improving metabolic parameters and reducing disease severity.
Product Specifications
CAS Number
1414248-06-8
Field of Research
Metabolism Research, Molecular Biology
Purity
99.93% (May vary between batches)
Smiles
FC (F) (F) C (O) (C1=CC=C (C=C1) C=2C=CC (=CC2C) CN3CCN (CC=4C=CN=CC4) CC3) C (F) (F) F
Molecular Formula
C27H27F6N3O
Molecular Weight
523.51
Storage Conditions
-20°C
Notes
For research use only.
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