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2'-O,4'-C-Methyleneuridine

2'-O,4'-C-Methyleneuridine is a bicyclic nucleoside analog featuring a locked C3'-endo sugar conformation. This structure enhances RNA affinity and nuclease resistance, making it valuable for oligonucleotide therapeutic research, including antisense and siRNA applications in vitro and in vivo.

Product Specifications

CAS Number

200435-92-3

Product Name Alternative

2' O,4' C Methyleneuridine, 2'-O,4'-C-Methyleneuridine, 2'O,4'CMethyleneuridine

Field of Research

Cell Biology, Molecular Biology

Purity

97.42% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15.61 mM) ; DMSO:100 mg/mL (390.3 mM)

Smiles

C (O) [C@@]12O[C@H] ([C@@] ([C@@H]1O) (OC2) [H]) N3C (=O) NC (=O) C=C3

Molecular Formula

C10H12N2O6

Molecular Weight

256.21

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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