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PRGL493

PRGL493 is a potent inhibitor of ACSL4, blocking arachidonoyl-CoA synthesis. It suppresses proliferation and migration in PC3 and MDA-MB-231 cells in vitro and inhibits tumor growth in a PC3 mouse xenograft model in vivo. This compound is a valuable tool for researching lipid metabolism in cancer biology and oncology.

Product Specifications

CAS Number

2479378-45-3

Product Name Alternative

PRGL 493, PRGL493, PRGL-493, long-chain acyl-CoA synthetase 4

Field of Research

Cell Biology

Purity

98.80% (May vary between batches)

Solubility

Chloroform:1 mg/mL (2.21 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.21 mM) ; DMSO:3.66 mg/mL (8.11 mM)

Smiles

CC (=O) NC1=NC (N2C (Nc3ccccc23) =N1) c1cn (nc1-c1ccc (C) o1) -c1ccccc1

Molecular Formula

C25H21N7O2

Molecular Weight

451.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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