PRGL493
PRGL493 is a potent inhibitor of ACSL4, blocking arachidonoyl-CoA synthesis. It suppresses proliferation and migration in PC3 and MDA-MB-231 cells in vitro and inhibits tumor growth in a PC3 mouse xenograft model in vivo. This compound is a valuable tool for researching lipid metabolism in cancer biology and oncology.
Product Specifications
CAS Number
2479378-45-3
Product Name Alternative
PRGL 493, PRGL493, PRGL-493, long-chain acyl-CoA synthetase 4
Field of Research
Cell Biology
Purity
98.80% (May vary between batches)
Solubility
Chloroform:1 mg/mL (2.21 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.21 mM) ; DMSO:3.66 mg/mL (8.11 mM)
Smiles
CC (=O) NC1=NC (N2C (Nc3ccccc23) =N1) c1cn (nc1-c1ccc (C) o1) -c1ccccc1
Molecular Formula
C25H21N7O2
Molecular Weight
451.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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