ML-345
Insulin-degrading enzyme (IDE) is a zinc-metallopeptidase crucial for insulin clearance and implicated in diabetes, Alzheimer's disease, and viral infection. ML-345 is a selective small-molecule inhibitor of IDE, targeting Cys819 with an EC50 of 188 nM and offering 10-fold selectivity, making it a valuable tool for studying IDE function in metabolic and neurological research.
Product Specifications
CAS Number
1632125-79-1
Field of Research
Protein Biochemistry
Purity
99.21% (May vary between batches)
Smiles
O=C1C2=CC (F) =CC=C2SN1C3=CC (=CC=C3N4CCOCC4) S (=O) (=O) N5CCOCC5
Molecular Formula
C21H22FN3O5S2
Molecular Weight
479.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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