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ML-345

Insulin-degrading enzyme (IDE) is a zinc-metallopeptidase crucial for insulin clearance and implicated in diabetes, Alzheimer's disease, and viral infection. ML-345 is a selective small-molecule inhibitor of IDE, targeting Cys819 with an EC50 of 188 nM and offering 10-fold selectivity, making it a valuable tool for studying IDE function in metabolic and neurological research.

Product Specifications

CAS Number

1632125-79-1

Field of Research

Protein Biochemistry

Purity

99.21% (May vary between batches)

Smiles

O=C1C2=CC (F) =CC=C2SN1C3=CC (=CC=C3N4CCOCC4) S (=O) (=O) N5CCOCC5

Molecular Formula

C21H22FN3O5S2

Molecular Weight

479.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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