CC-90005
CC-90005 is a potent, selective, and orally bioavailable inhibitor of protein kinase C-theta (PKC-θ), demonstrating an IC50 of 8 nM with significant selectivity over PKC-δ. It effectively suppresses T cell activation, as shown by the inhibition of IL-2 expression in vitro, making it a valuable tool for immunology and autoimmune disease research.
Product Specifications
CAS Number
1799574-70-1
Field of Research
Epigenetics & Chromatin, Signal Transduction
Smiles
CC (F) (F) COc1ncncc1CNc1ncc (C#N) c (N[C@@H]2CC[C@H] (O) C (C) (C) C2) n1
Molecular Formula
C21H27F2N7O2
Molecular Weight
447.48
Storage Conditions
-20°C
Notes
For research use only.
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