AAA
AAA is a GPR75 antagonist that elevates basal receptor levels and blocks 20-HETE-mediated GPR75 downregulation in PC3 cells. It inhibits 20-HETE-induced signaling through EGFR, NF-κB, and Akt, thereby reducing cell migration, making it a useful tool for studying oncogenic pathways in prostate cancer research.
Product Specifications
Smiles
[Na+].[Na+].OCCCC\C=C/CCCCCCC\C=C/CCCCC (=O) NC (CC ([O-]) =O) C ([O-]) =O
Molecular Formula
C24H39NNa2O6
Molecular Weight
483.55
Storage Conditions
-20°C
Notes
For research use only.
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