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AAA

AAA is a GPR75 antagonist that elevates basal receptor levels and blocks 20-HETE-mediated GPR75 downregulation in PC3 cells. It inhibits 20-HETE-induced signaling through EGFR, NF-κB, and Akt, thereby reducing cell migration, making it a useful tool for studying oncogenic pathways in prostate cancer research.

Product Specifications

Smiles

[Na+].[Na+].OCCCC\C=C/CCCCCCC\C=C/CCCCC (=O) NC (CC ([O-]) =O) C ([O-]) =O

Molecular Formula

C24H39NNa2O6

Molecular Weight

483.55

Storage Conditions

-20°C

Notes

For research use only.

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