AP39 Free base
AP39 is a mitochondria-targeted hydrogen sulfide donor used in research. It enhances porcine islet survival in culture and ameliorates doxorubicin-induced cardiac fibrosis in models by modulating mitophagy via the AMPK-ULK1-FUNDC1 pathway and suppressing pyroptosis.
Product Specifications
CAS Number
1429173-57-8
Product Name Alternative
AP39, AP-39, AP-39 Free base, AP 39, AP 39 Free base
Field of Research
Immunology & Inflammation
Purity
97.61% (May vary between batches)
Solubility
DMF:5 mg/mL (7.79 mM) ; DMSO:20 mg/mL (31.16 mM) ; Ethanol:16 mg/mL (24.93 mM) ; PBS (pH 7.2) :1 mg/mL (1.56 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (0.78 mM)
Smiles
O=C (OC=1C=CC (=CC1) C=2SSC (=S) C2) CCCCCCCCC[P+] (C=3C=CC=CC3) (C=4C=CC=CC4) C=5C=CC=CC5
Molecular Formula
C37H38O2PS3
Molecular Weight
641.87
Storage Conditions
-20°C
Notes
For research use only.
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