T-5342126
T-5342126 is a TLR4 antagonist that inhibits LPS-induced nitric oxide production in RAW 264.7 cells and reduces pro-inflammatory cytokine release in human whole blood. In vivo, it decreases ethanol consumption and microglial activation in the amygdala of ethanol-dependent mice, supporting its research use in neuroinflammation and addiction studies.
Product Specifications
CAS Number
956507-49-6
Field of Research
Immunology & Inflammation
Smiles
C (N1C (C) =C (CN (CC (COC2=CC=C (OCC) C=C2) O) C) C (C) =N1) C3=C (Cl) C=CC=C3
Molecular Formula
C25H32ClN3O3
Molecular Weight
457.99
Storage Conditions
-20°C
Notes
For research use only.
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