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T-5342126

T-5342126 is a TLR4 antagonist that inhibits LPS-induced nitric oxide production in RAW 264.7 cells and reduces pro-inflammatory cytokine release in human whole blood. In vivo, it decreases ethanol consumption and microglial activation in the amygdala of ethanol-dependent mice, supporting its research use in neuroinflammation and addiction studies.

Product Specifications

CAS Number

956507-49-6

Field of Research

Immunology & Inflammation

Smiles

C (N1C (C) =C (CN (CC (COC2=CC=C (OCC) C=C2) O) C) C (C) =N1) C3=C (Cl) C=CC=C3

Molecular Formula

C25H32ClN3O3

Molecular Weight

457.99

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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