CCG258208 hydrochloride
GRKs-IN-1 hydrochloride (Compound 14as) is a potent and selective GRK2 inhibitor (IC50=130 nM) derived from paroxetine. It demonstrates a significant, 100-fold improvement over paroxetine in enhancing cardiomyocyte contractility in vitro, making it a valuable research tool for studying heart failure and GPCR signaling pathways.
Product Specifications
Field of Research
Pharmacology & Drug Discovery
Smiles
FC (C=C1) =C (C (NCC2=CC=NN2) =O) C=C1[C@H]3[C@H] (COC4=CC5=C (OCO5) C=C4) CNCC3.Cl
Molecular Formula
C24H26ClFN4O4
Molecular Weight
488.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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