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CCG258208 hydrochloride

GRKs-IN-1 hydrochloride (Compound 14as) is a potent and selective GRK2 inhibitor (IC50=130 nM) derived from paroxetine. It demonstrates a significant, 100-fold improvement over paroxetine in enhancing cardiomyocyte contractility in vitro, making it a valuable research tool for studying heart failure and GPCR signaling pathways.

Product Specifications

Field of Research

Pharmacology & Drug Discovery

Smiles

FC (C=C1) =C (C (NCC2=CC=NN2) =O) C=C1[C@H]3[C@H] (COC4=CC5=C (OCO5) C=C4) CNCC3.Cl

Molecular Formula

C24H26ClFN4O4

Molecular Weight

488.94

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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