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JAK1-IN-8

JAK1-IN-8 is a potent and selective Janus kinase 1 (JAK1) inhibitor with an IC50 value below 500 nM. This small molecule is a valuable research tool for investigating JAK-STAT signaling pathways in both cellular and animal models of inflammation and autoimmune diseases.

Product Specifications

CAS Number

1973485-18-5

Product Name Alternative

JAK1IN8, JAK-1-IN-8, JAK1-IN-8, JAK1, JAK1 IN 8

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.36% (May vary between batches)

Solubility

DMSO:112.5 mg/mL (254.23 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.04 mM)

Smiles

Fc1cc (ccc1CN1CCS (=O) (=O) CC1) -c1cccc2nc (NC (=O) C3CC3) cn12

Molecular Formula

C22H23FN4O3S

Molecular Weight

442.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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