JAK1-IN-8
JAK1-IN-8 is a potent and selective Janus kinase 1 (JAK1) inhibitor with an IC50 value below 500 nM. This small molecule is a valuable research tool for investigating JAK-STAT signaling pathways in both cellular and animal models of inflammation and autoimmune diseases.
Product Specifications
CAS Number
1973485-18-5
Product Name Alternative
JAK1IN8, JAK-1-IN-8, JAK1-IN-8, JAK1, JAK1 IN 8
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.36% (May vary between batches)
Solubility
DMSO:112.5 mg/mL (254.23 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.04 mM)
Smiles
Fc1cc (ccc1CN1CCS (=O) (=O) CC1) -c1cccc2nc (NC (=O) C3CC3) cn12
Molecular Formula
C22H23FN4O3S
Molecular Weight
442.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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