EGFR-IN-99
EGFR-IN-99 (JBJ-03-142-02) is a selective small molecule inhibitor targeting EGFR and HER2 exon 20 insertion mutations. It demonstrates potent antiproliferative activity in non-small cell lung cancer (NSCLC) cell lines and has shown efficacy in preclinical in vivo tumor models, supporting its use as a research tool for targeted oncology studies.
Product Specifications
CAS Number
2068806-31-3
Product Name Alternative
JBJ 03 142 02, JBJ0314202, JBJ-03-142-02, HER2, EGFR
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
97.07% (May vary between batches)
Solubility
DMSO:1 mg/mL (2.05 mM)
Smiles
O=C (C=C) NC1=CC=CC (=C1) N (C (=O) OCC2=CC=C (F) C=C2) C3=NC (=NC=C3) NC=4C=NN (C4) C
Molecular Formula
C25H22FN7O3
Molecular Weight
487.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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