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EGFR-IN-99

EGFR-IN-99 (JBJ-03-142-02) is a selective small molecule inhibitor targeting EGFR and HER2 exon 20 insertion mutations. It demonstrates potent antiproliferative activity in non-small cell lung cancer (NSCLC) cell lines and has shown efficacy in preclinical in vivo tumor models, supporting its use as a research tool for targeted oncology studies.

Product Specifications

CAS Number

2068806-31-3

Product Name Alternative

JBJ 03 142 02, JBJ0314202, JBJ-03-142-02, HER2, EGFR

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Purity

97.07% (May vary between batches)

Solubility

DMSO:1 mg/mL (2.05 mM)

Smiles

O=C (C=C) NC1=CC=CC (=C1) N (C (=O) OCC2=CC=C (F) C=C2) C3=NC (=NC=C3) NC=4C=NN (C4) C

Molecular Formula

C25H22FN7O3

Molecular Weight

487.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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